Scientists Reprogram Adult Bone or Fat Cells to Form Stem Cells that Could Potentially Regenerate any Damaged Tissue in the body
This recent advancement in regenerative health, science and technology have been contributed to humanity by the team of Australian Scientists and Researchers, John Pimanda, Associate Professor of Medicine and Stem Cell Biology; Ralph Mobbs, Neurosurgeon at the Prince of Wales Hospital; Conjoint Lecturer; and Vashe Chandrakanthan, Researcher, Renenerative Medicine, UNSW Australia.
by Susan Price, TLB Contributing Writer/Analyst
We’ve all heard that the human body has the capability of healing and regenerating itself, try and wrap your head around one of the newest medical technologies discovered whereby a healthier existence for the human species and evolutionary process can and will transform the health and wellness of mankind.
This new medical marvel of new stem cell treatment uses fat tissue to help heal a number of diseases including MS, MD, ALS, RA, Parkinson’s. Doctors say it is also showing great potential with repairing joints COPD and Asthma. Increasing the quality of life and promoting longevity.
The extraction and transformation process of fat cells into stem cells to heal the body have existed quietly in the laboratory for some time and now with technology reaching new heights, the ability to heal all wounded areas of the human body, including the inflammation process are a huge contribution to humanity on the world health scale. Scientists have conceived a way to reprogram ordinary grownup stem cells into caused pluripotent stem cells (iPS) a form of stem cell that’s more flexible than multipotent stem cells, yet require the usage of viruses in order for cells to be “reset”.
The fat cells are collected from the human body, then converted into adult stem cells with the help of growth factors, five-Azacytidine (AZA); and platelet-derived boom component-AB (PDGF-AB) for two days. Adult stem cells are then induced to become pluripotent stem cells (iPSC).
This kick-started the method of dedifferentiation, which basically way it started out to revert them to a multipotent stem cell nation. The cells were then kept in PDGF-AB for a few weeks while they slowly changed into stem cells. These cells can be used to repair any types of tissues in the body.
These cells also provide an anti-inflammatory effect which aids in the healing process. These stem cells can be used for breast reconstruction after surgery for breast cancer, whereby, patients receive their own cells so there is no risk of immune rejection.
Imagine your own fat derived stem cells can now be used to prevent premature cell death, what a revolutionary concept that can and will eventually change health care as we know it as these cells can be reprogrammed to form functioning blood vessels. IPS cells can also suppress immune responses in autoimmune disorders, as they can be induced to differentiate into nerve cells, offering a new and effective treatment for neurodegenerative diseases. Surely this would prove over a period of time, a decline in the elderly population affected by Alzheimer’s and Parkinson’s diseases.
There are different techniques used to deliver stem cells into the right location as stem cells are infused into the bloodstream and injected into localized tissues. The stem cells are then attracted to signals from areas of inflammation, these signals trigger stem cells to differentiate and turn into specialized cells, specialized cells begin to integrate with the target tissues or organs. Fat cells are more abundant and accessible source for regenerative therapies.
Another great moral concept to note is there are no ethical issues involved with using fat derived stem cells. Fat contains up to 90% more viable cells than that of bone marrow. The conception of viable cells in fat tissue remains unaffected by age. Fat cells can be turned into iPS cells twice as quickly as skin cells.
Techniques used for fat cells extraction are easier and more efficient, the process involves a mini liposuction to obtain the patients own fat, usually from the abdominal or flank areas, the procedure is performed without general anesthesia and is relatively painless. Stem cells retrieved from fats are more easily cultured and grow more rapidly than those harvested from bone marrow.
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About (TLB) Contributing Writer Susan Price
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